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Target has curated data in GtoImmuPdb
Target id: 1715
Nomenclature: Interleukin-12 receptor, β1 subunit
Family: IL-12 receptor family
Annotation status:
Awaiting annotation
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| Quaternary Structure: Complexes |
| Interleukin-12 receptor |
| Interleukin-23 receptor |
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | 1 | 662 | 19p13.11 | IL12RB1 | interleukin 12 receptor subunit beta 1 | |
| Mouse | 1 | 738 | 8 34.21 cM | Il12rb1 | interleukin 12 receptor, beta 1 | |
| Rat | - | - | Il12rb1 | interleukin 12 receptor subunit beta 1 | ||
| Previous and Unofficial Names |
| CD212 | interleukin 12 receptor, beta 1 | interleukin 12 receptor |
| Database Links |
|
| Alphafold | P42701 (Hs), Q60837 (Mm) |
| CATH/Gene3D | 2.60.40.10 |
| ChEMBL Target | CHEMBL4523226 (Hs) |
| Ensembl Gene | ENSG00000096996 (Hs), ENSMUSG00000000791 (Mm), ENSRNOG00000019216 (Rn) |
| Entrez Gene | 3594 (Hs), 16161 (Mm) |
| Human Protein Atlas | ENSG00000096996 (Hs) |
| KEGG Gene | hsa:3594 (Hs), mmu:16161 (Mm) |
| OMIM | 601604 (Hs) |
| Pharos | P42701 (Hs) |
| UniProtKB | P42701 (Hs), Q60837 (Mm) |
| Wikipedia | IL12RB1 (Hs) |
| Immunopharmacology Comments |
| This protein is a subunit of both the IL-12 and IL-23 cytokine receptors. |
Laura E. Kilpatrick.
Last modified on 22/03/2017.
The citation format for the published version of this page will be:
Laura E. Kilpatrick.
IL-12 receptor family: Interleukin-12 receptor, β1 subunit. Last modified on 22/03/2017. Accessed on 12/09/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1715.
