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Abbreviated name: NRG-1
Synonyms: breast cancer cell differentiation factor p45 | glial growth factor (GGF) | heregulin | Neu differentiation factor (NDF)
Compound class:
Endogenous peptide in human, mouse or rat
Species: Human
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Jones JT, Akita RW, Sliwkowski MX. (1999)
Binding specificities and affinities of egf domains for ErbB receptors. FEBS Lett, 447 (2-3): 227-31. [PMID:10214951] |
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2. Tzahar E, Pinkas-Kramarski R, Moyer JD, Klapper LN, Alroy I, Levkowitz G, Shelly M, Henis S, Eisenstein M, Ratzkin BJ et al.. (1997)
Bivalence of EGF-like ligands drives the ErbB signaling network. EMBO J, 16 (16): 4938-50. [PMID:9305636] |
