neuregulin-1 [Ligand Id: 5027] activity data from GtoPdb

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  • erb-b2 receptor tyrosine kinase 3 in Human [GtoPdb: 1798] [UniProtKB: P21860]
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  • erb-b2 receptor tyrosine kinase 4 in Human [GtoPdb: 1799] [UniProtKB: Q15303]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
erb-b2 receptor tyrosine kinase 3 in Human [GtoPdb: 1798] [UniProtKB: P21860]
GtoPdb - - 8.89 pKd 1.3 nM Kd EMBO J (1997) 16: 4938-50 [PMID:9305636]
GtoPdb - - 8.27 pIC50 5.4 nM IC50 FEBS Lett (1999) 447: 227-31 [PMID:10214951]
GtoPdb - - 9.26 pIC50 0.55 nM IC50 FEBS Lett (1999) 447: 227-31 [PMID:10214951]
erb-b2 receptor tyrosine kinase 4 in Human [GtoPdb: 1799] [UniProtKB: Q15303]
GtoPdb - - 9.15 pKd 0.7 nM Kd EMBO J (1997) 16: 4938-50 [PMID:9305636]
GtoPdb - - 6.29 pIC50 510 nM IC50 FEBS Lett (1999) 447: 227-31 [PMID:10214951]
GtoPdb - - 8.29 pIC50 5.1 nM IC50 FEBS Lett (1999) 447: 227-31 [PMID:10214951]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.