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Target has curated data in GtoImmuPdb
Target id: 2930
Nomenclature: CD209 molecule
Abbreviated Name: DC-SIGN
Family: C-type lectin-like receptors (CLRs)
Annotation status:
Awaiting annotation
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Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | 1 | 404 | 19p13.2 | CD209 | CD209 molecule | |
| Gene and Protein Information Comments | ||||||
| A number of splice variants, encoding different protein isoforms of human CD209 have been identified. The mouse has five CD209 homologs and there are no rat homologs. | ||||||
| Previous and Unofficial Names |
| CDSIGN | CLEC4L |
| Database Links |
|
| Alphafold | Q9NNX6 (Hs) |
| CATH/Gene3D | 3.10.100.10 |
| ChEMBL Target | CHEMBL1795114 (Hs) |
| Ensembl Gene | ENSG00000090659 (Hs) |
| Entrez Gene | 30835 (Hs) |
| Human Protein Atlas | ENSG00000090659 (Hs) |
| KEGG Gene | hsa:30835 (Hs) |
| OMIM | 604672 (Hs) |
| Pharos | Q9NNX6 (Hs) |
| RefSeq Nucleotide | NM_021155 (Hs) |
| RefSeq Protein | NP_066978 (Hs) |
| UniProtKB | Q9NNX6 (Hs) |
| Wikipedia | CD209 (Hs) |
| Immunopharmacology Comments |
| DC-SIGN is a pathogen-recognition receptor involved in initiating the primary immune response to various viral and bacterial pathogens, as well as antigen presentation and initiation of the adaptive immune response. |
| Cell Type Associations | ||
|
| General Comments |
| DC-SIGN (CD209) is a pathogen-recognition receptor expressed on the surface of immature dendritic cells. |
Last modified on 16/07/2020.
The citation format for the published version of this page will be:
C-type lectin-like receptors (CLRs): CD209 molecule. Last modified on 16/07/2020. Accessed on 12/09/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2930.
