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Target has curated data in GtoImmuPdb
Target id: 1728
Nomenclature: Interleukin 10 receptor, β subunit
Family: IL-10 receptor family
Annotation status:
Awaiting annotation
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| Quaternary Structure: Complexes |
| Interleukin-10 receptor |
| Interleukin-22α1/10β heteromer |
| Interferon-λ receptor 1 |
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | 1 | 325 | 21q22.11 | IL10RB | interleukin 10 receptor subunit beta | |
| Mouse | 1 | 349 | 16 52.87 cM | Il10rb | interleukin 10 receptor, beta | |
| Rat | - | - | Il10rb | interleukin 10 receptor subunit beta | ||
| Previous and Unofficial Names |
| CRF2-4 | CRFB4 | IL-10R2 | Il10rb | Interleukin-10 β | interleukin 10 receptor, beta | interleukin 10 receptor |
| Database Links |
|
| Alphafold | Q08334 (Hs), Q61190 (Mm) |
| CATH/Gene3D | 2.60.40.10 |
| ChEMBL Target | CHEMBL3831284 (Hs), CHEMBL4804254 (Hs), CHEMBL4804251 (Hs) |
| Ensembl Gene | ENSG00000243646 (Hs), ENSMUSG00000022969 (Mm), ENSRNOG00000028638 (Rn) |
| Entrez Gene | 3588 (Hs), 16155 (Mm), 304091 (Rn) |
| Human Protein Atlas | ENSG00000243646 (Hs) |
| KEGG Gene | hsa:3588 (Hs), mmu:16155 (Mm), rno:304091 (Rn) |
| OMIM | 123889 (Hs) |
| Pharos | Q08334 (Hs) |
| UniProtKB | Q08334 (Hs), Q61190 (Mm) |
| Wikipedia | IL10RB (Hs) |
| Immunopharmacology Comments |
| Interleukin 10 receptor, β subunit is a component of the functional receptor heterodimers for interleukins 10 and 22 and for interferons λ1, λ2 and λ3. |
Last modified on 06/04/2017.
The citation format for the published version of this page will be:
IL-10 receptor family: Interleukin 10 receptor, β subunit. Last modified on 06/04/2017. Accessed on 12/09/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1728.
