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Not curated in GtoImmuPdb
Target id: 95
Nomenclature: GPR25
Family: Class A Orphans with emerging pharmacology
Annotation status:
Annotated and reviewed, awaiting update
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Gene and Protein Information  |
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| class A G protein-coupled receptor | ||||||
| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | 7 | 361 | 1q32.1 | GPR25 | G protein-coupled receptor 25 | 1 |
| Mouse | 7 | 358 | 1 E4 | Gpr25 | G protein-coupled receptor 25 | |
| Rat | 7 | 345 | 13q13 | Gpr25 | G protein-coupled receptor 25 | |
| Database Links |
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| Specialist databases | |
| GPCRdb | gpr25_human (Hs), gpr25_mouse (Mm) |
| Other databases | |
| Alphafold | O00155 (Hs), P0C5I1 (Mm) |
| ChEMBL Target | CHEMBL4523858 (Hs) |
| Ensembl Gene | ENSG00000170128 (Hs), ENSMUSG00000052759 (Mm), ENSRNOG00000008603 (Rn) |
| Entrez Gene | 2848 (Hs), 383563 (Mm), 363993 (Rn) |
| Human Protein Atlas | ENSG00000170128 (Hs) |
| KEGG Gene | hsa:2848 (Hs), mmu:383563 (Mm), rno:363993 (Rn) |
| OMIM | 602174 (Hs) |
| Pharos | O00155 (Hs) |
| RefSeq Nucleotide | NM_005298 (Hs), NM_001101516 (Mm) |
| RefSeq Protein | NP_005289 (Hs), NP_001094986 (Mm) |
| UniProtKB | O00155 (Hs), P0C5I1 (Mm) |
| Wikipedia | GPR25 (Hs) |
| Tissue Distribution Comments | |
| Northern blot analysis of poly(A)+ mRNA extracted from human tissues revealed no expression of GPR25 in liver and brain regions examined (basal forebrain, frontal cortex, thalamus, hypothalamus, amygdala, caudate, putamen, hippocampus, midbrain, medulla, cerebellum and pituitary) [1]. |
| Expression Datasets |
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| Biologically Significant Variants
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