β-catenin

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Ligands
β-catenin (Human)

GtoPdb Ligand ID: 5371

Synonyms: catenin beta-1

Compound class: Endogenous peptide in human, mouse or rat

Species: Human

References
1. Wang Z, Zhao T, Zhang S, Wang J, Chen Y, Zhao H, Yang Y, Shi S, Chen Q, Liu K. (2021) The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy. Biomark Res, 9 (1): 68. [PMID:34488905]
2. White BH, La DS, Alfaro-Lopez LJ, Ortet PC, Cappicci SI, Li Z, Mcgee JH, Tremblay MR, Verdine GL, Si Y et al.. (2022) Stapled peptides and methods thereof. Patent number: WO2022261257A1. Assignee: Fog Pharmaceuticals, Inc.. Priority date: 08/06/2022. Publication date: 15/12/2022.
3. Zhang H, Liu C, Chen Q, Shen LA, Xiao W, Li J, Wang Y, Zhu D, Zhang Q, Li J. (2023) Discovery of Novel 3-Phenylpiperidine Derivatives Targeting the β-Catenin/B-Cell Lymphoma 9 Interaction as a Single Agent and in Combination with the Anti-PD-1 Antibody for the Treatment of Colorectal Cancer. J Med Chem, 66 (2): 1349-1379. [PMID:36630177]

References

1. Wang Z, Zhao T, Zhang S, Wang J, Chen Y, Zhao H, Yang Y, Shi S, Chen Q, Liu K. (2021)
The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy.
Biomark Res, 9 (1): 68. [PMID:34488905]

2. White BH, La DS, Alfaro-Lopez LJ, Ortet PC, Cappicci SI, Li Z, Mcgee JH, Tremblay MR, Verdine GL, Si Y et al.. (2022)
Stapled peptides and methods thereof.
Patent number: WO2022261257A1. Assignee: Fog Pharmaceuticals, Inc.. Priority date: 08/06/2022. Publication date: 15/12/2022.

3. Zhang H, Liu C, Chen Q, Shen LA, Xiao W, Li J, Wang Y, Zhu D, Zhang Q, Li J. (2023)
Discovery of Novel 3-Phenylpiperidine Derivatives Targeting the β-Catenin/B-Cell Lymphoma 9 Interaction as a Single Agent and in Combination with the Anti-PD-1 Antibody for the Treatment of Colorectal Cancer.
J Med Chem, 66 (2): 1349-1379. [PMID:36630177]