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mitochondrial peptide fMFADRW   Click here for help

GtoPdb Ligand ID: 14144

Compound class: Peptide
Comment: This is an endogenous human mitochondrial cryptic hexapeptide with an N-terminal fMet [3]. It corresponds to the N terminus of cytochrome c oxidase subunit I. fMFADRW is a formyl peptide receptor agonist.
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
FPR1 Hs Agonist Agonist - - - 1,3
⤷ [1,3]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Potency order of endogenous ligands at FPR1 mitochondrial peptde fMMYALF > fMLKLIV > mitochondrial peptide fMFADRW > annexin I-(2-26) (ANXA1, P04083) 1-2