OMN6

GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

Home
Ligands
OMN6

GtoPdb Ligand ID: 14120

Compound class: Peptide

Comment: OMN6 is a cyclic antimicrobial peptide based on the sequence of cecropin A, with activity against drug-resistant Gram-negative bacteria [1].

Summary
Biological activity
Clinical data
References
Structure

References
1. Mandel S, Michaeli J, Nur N, Erbetti I, Zazoun J, Ferrari L, Felici A, Cohen-Kutner M, Bachnoff N. (2021) OMN6 a novel bioengineered peptide for the treatment of multidrug resistant Gram negative bacteria. Sci Rep, 11 (1): 6603. [PMID:33758343]
2. Michaeli J, Mandel S, Maximov S, Zazoun J, Savoia P, Kothari N, Valmont T, Ferrari L, Duncan LR, Hawser S et al.. (2022) In Vitro and In Vivo Antimicrobial Activity of the Novel Peptide OMN6 against Multidrug-Resistant Acinetobacter baumannii. Antibiotics (Basel), 11 (9). [PMID:36139979]

References

1. Mandel S, Michaeli J, Nur N, Erbetti I, Zazoun J, Ferrari L, Felici A, Cohen-Kutner M, Bachnoff N. (2021)
OMN6 a novel bioengineered peptide for the treatment of multidrug resistant Gram negative bacteria.
Sci Rep, 11 (1): 6603. [PMID:33758343]

2. Michaeli J, Mandel S, Maximov S, Zazoun J, Savoia P, Kothari N, Valmont T, Ferrari L, Duncan LR, Hawser S et al.. (2022)
In Vitro and In Vivo Antimicrobial Activity of the Novel Peptide OMN6 against Multidrug-Resistant Acinetobacter baumannii.
Antibiotics (Basel), 11 (9). [PMID:36139979]