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DPK-060   Click here for help

GtoPdb Ligand ID: 14113

Synonyms: GKH17-WWW
Compound class: Peptide
Comment: DPK-060 is a synthetic antimicrobial peptide, structurally derived from the human protein kininogen, that was designed to increase antibacterial potency using hydrophobic end tagging [1].
No information available.
Summary of Clinical Use Click here for help
DPK-060 (topical formulation) has completed Phase 2 studies to evaluate antimicrobial efficacy in patients with atopic dermatitis (NCT01522391) or with acute external otitis (NCT01447017).
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT01447017 A Study of DPK-060 to Investigate Clinical Safety and Efficacy in Patients With Acute External Otitis Phase 2 Interventional DermaGen AB
NCT01522391 A Randomized, Double-blinded Placebo-controlled Study to Investigate Antimicrobial Efficacy and Safety Following Topical Application of DPK-060 Phase 1/Phase 2 Interventional DermaGen AB