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Compound class:
Peptide
Comment: BmTx2 is a 37 amino acid toxin from the venom of the Chinese scorpion Buthus martensi [2]. It is a potassium channel blocker. We provide the amino acid sequence for the mature peptide without its signal peptide sequence.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Blanc E, Romi-Lebrun R, Bornet O, Nakajima T, Darbon H. (1998)
Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels. Biochemistry, 37 (36): 12412-8. [PMID:9730813] |
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2. Dai L, Wu JJ, Gu YH, Lan ZD, Ling MH, Chi CW. (2000)
Genomic organization of three novel toxins from the scorpion Buthus martensi Karsch that are active on potassium channels. Biochem J, 346 Pt 3 (Pt 3): 805-9. [PMID:10698710] |
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3. Romi-Lebrun R, Lebrun B, Martin-Eauclaire MF, Ishiguro M, Escoubas P, Wu FQ, Hisada M, Pongs O, Nakajima T. (1997)
Purification, characterization, and synthesis of three novel toxins from the Chinese scorpion Buthus martensi, which act on K+ channels. Biochemistry, 36 (44): 13473-82. [PMID:9354615] |
