ChEMBL ligand: CHEMBL4536031
ATPase family AAA domain containing 2/ATPase family AAA domain-containing protein 2 in Human [ChEMBL: CHEMBL2150837] [GtoPdb: 2719] [UniProtKB: Q6PL18] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ATPase family AAA domain containing 2/ATPase family AAA domain-containing protein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2150837] [GtoPdb: 2719] [UniProtKB: Q6PL18]
GtoPdb	Measuring displacement of a tetra-acetylated peptide histone H4 N-terminal peptide from ATAD2 in a BromoScan assay	-	6.94	pKd	115	nM	Kd	ACS Chem Biol (2017) 12: 2730-2736 [PMID:29043777]
ChEMBL	Induction of ATAD2 bromodomain (unknown origin) dimerization	B	6.78	pIC50	166	nM	IC50	J Med Chem (2018) 61: 9004-9029 [PMID:29851477]
ChEMBL	Inhibition of N-terminal Hexahistidine-GST-tagged human ATAD2 bromodomain expressed in Escherichia coli BL21 (DE3) Rosetta cells incubated for 1 hr by FRET analysis	B	7.66	pIC50	22	nM	IC50	J Med Chem (2024) 67: 864-884 [PMID:38197367]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]