Adhesion GPCRs are structurally identified on the basis of a large extracellular region, similar to the Class B GPCR, but which is linked to the 7TM region by a GPCR autoproteolysis-inducing (GAIN) domain [8] containing a GPCR proteolysis site (GPS). The N-terminal extracellular region often shares structural homology with adhesive domains (e.g. cadherins, immunolobulin, lectins) facilitating inter- and matricellular interactions and leading to the term adhesion GPCR [57,210]. Several receptors have been suggested to function as mechanosensors [27,139,142,157,200]. Cryo-EM structures of the 7-transmembrane domain of several adhesion GPCRs have been determined recently [17,109,141-142,148-149,203,222]. The nomenclature of these receptors was revised in 2015 as recommended by NC-IUPHAR and the Adhesion GPCR Consortium [67].

* Key recommended reading is highlighted with an asterisk

* Bassilana F, Nash M, Ludwig MG. (2019) Adhesion G protein-coupled receptors: opportunities for drug discovery. Nat Rev Drug Discov, 18 (11): 869-884. [PMID:31462748]

Dates AN, Jones DTD, Smith JS, Skiba MA, Rich MF, Burruss MM, Kruse AC, Blacklow SC. (2024) Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors. Cell Chem Biol, 31 (8): 1542-1553.e4. [PMID:38608683]

* Gupta C, Bernadyn TF, Tall GG. (2023) Structural clarity is brought to adhesion G protein-coupled receptor tethered agonism. Basic Clin Pharmacol Toxicol, 133 (4): 295-300. [PMID:36585032]

* Hamann J, Aust G, Araç D, Engel FB, Formstone C, Fredriksson R, Hall RA, Harty BL, Kirchhoff C, Knapp B et al.. (2015) International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacol Rev, 67 (2): 338-67. [PMID:25713288]

* Kleinau G, Ali AH, Wiechert F, Szczepek M, Schmidt A, Spahn CMT, Liebscher I, Schöneberg T, Scheerer P. (2023) Intramolecular activity regulation of adhesion GPCRs in light of recent structural and evolutionary information. Pharmacol Res, 197: 106971. [PMID:38032292]

* Langenhan T, Aust G, Hamann J. (2013) Sticky signaling--adhesion class G protein-coupled receptors take the stage. Sci Signal, 6 (276): re3. [PMID:23695165]

Liebscher I, Schöneberg T. (2016) Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs. Handb Exp Pharmacol, 234: 111-125. [PMID:27832486]

* Liessmann F, von Bredow L, Meiler J, Liebscher I. (2024) Targeting adhesion G protein-coupled receptors. Current status and future perspectives. Structure, 32 (12): 2188-2205. [PMID:39520987]

* Monk KR, Hamann J, Langenhan T, Nijmeijer S, Schöneberg T, Liebscher I. (2015) Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms. Mol Pharmacol, 88 (3): 617-23. [PMID:25956432]

* Purcell RH, Hall RA. (2018) Adhesion G Protein-Coupled Receptors as Drug Targets. Annu Rev Pharmacol Toxicol, 58: 429-449. [PMID:28968187]

Wang N, Qian Y, Xia R, Zhu X, Xiong Y, Zhang A, Guo C, He Y. (2023) Structural basis of CD97 activation and G-protein coupling. Cell Chem Biol, 30 (11): 1343-1353.e5. [PMID:37673067]

Yona S, Lin HH, Siu WO, Gordon S, Stacey M. (2008) Adhesion-GPCRs: emerging roles for novel receptors. Trends Biochem Sci, 33 (10): 491-500. [PMID:18789697]

1. Abdulkareem NM, Bhat R, Castillo M, Jung SY, Vasaikar S, Nanda S, Ruiz A, Shea M, Cao W, Veeraraghavan J et al.. (2025) Interactions between ADGRF1 (GPR110) and extracellular matrix proteins govern its effects on tumorigenesis in HER2-positive breast cancer. Br J Pharmacol, 182 (11): 2524-2541. [PMID:39965212]

2. Abdulkareem NM, Bhat R, Qin L, Vasaikar S, Gopinathan A, Mitchell T, Shea MJ, Nanda S, Thangavel H, Zhang B et al.. (2021) A novel role of ADGRF1 (GPR110) in promoting cellular quiescence and chemoresistance in human epidermal growth factor receptor 2-positive breast cancer. FASEB J, 35 (7): e21719. [PMID:34110646]

3. Ackerman SD, Luo R, Poitelon Y, Mogha A, Harty BL, D'Rozario M, Sanchez NE, Lakkaraju AKK, Gamble P, Li J et al.. (2018) GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med, 215 (3): 941-961. [PMID:29367382]

4. Akter R, Kim K, Kwon HY, Kim Y, Eom YW, Cho HM, Cho MY. (2022) EMR1/ADGRE1 Expression in Cancer Cells Upregulated by Tumor-Associated Macrophages Is Related to Poor Prognosis in Colorectal Cancer. Biomedicines, 10 (12). [PMID:36551877]

5. Allen-Brady K, Clayton F, Hazel MW, Stevens J, Pyne AL, Pletneva MA, Cessna M, Stubben C, Robson J, Fang J et al.. (2025) Overlap of Genomic and Transcriptomic Genes Identified in Familial Eosinophilic Esophagitis. Gastroenterology, 168 (6): 1101-1113.e18. [PMID:39914776]

6. An W, Lin H, Ma L, Zhang C, Zheng Y, Cheng Q, Ma C, Wu X, Zhang Z, Zhong Y et al.. (2022) Progesterone activates GPR126 to promote breast cancer development via the Gi pathway. Proc Natl Acad Sci U S A, 119 (15): e2117004119. [PMID:35394864]

7. Anderson PJ, Xiao P, Zhong Y, Kaakati A, Alfonso-DeSouza J, Zhang T, Zhang C, Yu K, Qi L, Ding W et al.. (2025) β-Arrestin Condensates Regulate G Protein-Coupled Receptor Function. bioRxiv, Preprint. [PMID:40236194]

8. Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT. (2012) A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. EMBO J, 31 (6): 1364-78. [PMID:22333914]

9. Arcos-Burgos M, Jain M, Acosta MT, Shively S, Stanescu H, Wallis D, Domené S, Vélez JI, Karkera JD, Balog J et al.. (2010) A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication. Mol Psychiatry, 15 (11): 1053-66. [PMID:20157310]

10. Arcos-Burgos M, Vélez JI, Martinez AF, Ribasés M, Ramos-Quiroga JA, Sánchez-Mora C, Richarte V, Roncero C, Cormand B, Fernández-Castillo N et al.. (2019) ADGRL3 (LPHN3) variants predict substance use disorder. Transl Psychiatry, 9 (1): 42. [PMID:30696812]

11. Atigan A, Tan S, Cetin H, Guler OT, Ozdamar S, Karakaya YA. (2022) CD97 expression level and its effect on cell adhesion in Preeclampsia. BMC Pregnancy Childbirth, 22 (1): 967. [PMID:36572878]

12. Aust G, Hamann J, Schilling N, Wobus M. (2003) Detection of alternatively spliced EMR2 mRNAs in colorectal tumor cell lines but rare expression of the molecule in colorectal adenocarcinomas. Virchows Arch, 443 (1): 32-7. [PMID:12761622]

13. Aust G, Wandel E, Boltze C, Sittig D, Schütz A, Horn LC, Wobus M. (2006) Diversity of CD97 in smooth muscle cells. Cell Tissue Res, 324 (1): 139-47. [PMID:16408199]

14. Bae JS, Lee JW, Yoo JE, Joung JG, Yoo KH, Koo HH, Song YM, Sung KW. (2020) Genome-Wide Association Study for the Identification of Novel Genetic Variants Associated with the Risk of Neuroblastoma in Korean Children. Cancer Res Treat, 52 (4): 1251-1261. [PMID:32599975]

15. Bagger SM, Schihada H, Walser ALS, Drzazga AK, Grätz L, Palmisano T, Kuhn CK, Mavri M, Mølleskov-Jensen A-S, Tall GG et al.. (2025) Complex G-protein signaling of the adhesion GPCR, ADGRA3. JBC, Online ahead of rint. DOI: 10.1016/j.jbc.2025.108441

16. Bandekar SJ, Garbett K, Kordon SP, Dintzner EE, Li J, Shearer T, Sando RC, Araç D. (2025) Structural basis for regulation of CELSR1 by a compact module in its extracellular region. Nat Commun, 16 (1): 3972. [PMID:40295529]

17. Barros-Álvarez X, Nwokonko RM, Vizurraga A, Matzov D, He F, Papasergi-Scott MM, Robertson MJ, Panova O, Yardeni EH, Seven AB et al.. (2022) The tethered peptide activation mechanism of adhesion GPCRs. Nature, 604 (7907): 757-762. [PMID:35418682]

18. Bayin NS, Frenster JD, Kane JR, Rubenstein J, Modrek AS, Baitalmal R, Dolgalev I, Rudzenski K, Scarabottolo L, Crespi D et al.. (2016) GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth. Oncogenesis, 5 (10): e263. [PMID:27775701]

19. Beall SA, Boekelheide K, Johnson KJ. (2005) Hybrid GPCR/cadherin (Celsr) proteins in rat testis are expressed with cell type specificity and exhibit differential Sertoli cell-germ cell adhesion activity. J Androl, 26 (4): 529-38. [PMID:15955893]

20. Bhudia N, Desai S, King N, Ancellin N, Grillot D, Barnes AA, Dowell SJ. (2020) Author Correction: G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody. Sci Rep, 10 (1): 5097. [PMID:32184438]

21. Bhudia N, Desai S, King N, Ancellin N, Grillot D, Barnes AA, Dowell SJ. (2020) G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody. Sci Rep, 10 (1): 1004. [PMID:31969668]

22. Bianchi E, Sun Y, Almansa-Ordonez A, Woods M, Goulding D, Martinez-Martin N, Wright GJ. (2021) Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit. Nat Commun, 12 (1): 1251. [PMID:33623007]

23. Bjarnadóttir TK, Geirardsdóttir K, Ingemansson M, Mirza MA, Fredriksson R, Schiöth HB. (2007) Identification of novel splice variants of Adhesion G protein-coupled receptors. Gene, 387 (1-2): 38-48. [PMID:17056209]

24. Bohnekamp J, Schöneberg T. (2011) Cell adhesion receptor GPR133 couples to Gs protein. J Biol Chem, 286 (49): 41912-6. [PMID:22025619]

25. Bolliger MF, Martinelli DC, Südhof TC. (2011) The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins. Proc Natl Acad Sci USA, 108 (6): 2534-9. [PMID:21262840]

26. Boucard AA, Ko J, Südhof TC. (2012) High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex. J Biol Chem, 287 (12): 9399-413. [PMID:22262843]

27. Boyden SE, Desai A, Cruse G, Young ML, Bolan HC, Scott LM, Eisch AR, Long RD, Lee CC, Satorius CL et al.. (2016) Vibratory Urticaria Associated with a Missense Variant in ADGRE2. N Engl J Med, 374 (7): 656-63. [PMID:26841242]

28. Bradley EC, Cunningham RL, Wilde C, Morgan RK, Klug EA, Letcher SM, Schöneberg T, Monk KR, Liebscher I, Petersen SC. (2019) In vivo identification of small molecules mediating Gpr126/Adgrg6 signaling during Schwann cell development. Ann N Y Acad Sci, 1456 (1): 44-63. [PMID:31529518]

29. Bridges JP, Ludwig MG, Mueller M, Kinzel B, Sato A, Xu Y, Whitsett JA, Ikegami M. (2013) Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size. Am J Respir Cell Mol Biol, 49 (3): 348-57. [PMID:23590306]

30. Brown K, Filuta A, Ludwig MG, Seuwen K, Jaros J, Vidal S, Arora K, Naren AP, Kandasamy K, Parthasarathi K et al.. (2017) Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling. JCI Insight, 2 (11). [PMID:28570277]

31. Caminschi I, Lucas KM, O'Keeffe MA, Hochrein H, Laâbi Y, Köntgen F, Lew AM, Shortman K, Wright MD. (2001) Molecular cloning of F4/80-like-receptor, a seven-span membrane protein expressed differentially by dendritic cell and monocyte-macrophage subpopulations. J Immunol, 167 (7): 3570-6. [PMID:11564768]

32. Caminschi I, Vandenabeele S, Sofi M, McKnight AJ, Ward N, Brodnicki TC, Toy T, Lahoud M, Maraskovsky E, Shortman K, Wright MD. (2006) Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE. DNA Seq, 17: 8-14. [PMID:16753812]

33. Carr JC, Boese EA, Spanheimer PM, Dahdaleh FS, Martin M, Calva D, Schafer B, Thole DM, Braun T, O'Dorisio TM et al.. (2012) Differentiation of small bowel and pancreatic neuroendocrine tumors by gene-expression profiling. Surgery, 152 (6): 998-1007. [PMID:23158174]

34. Chang GW, Davies JQ, Stacey M, Yona S, Bowdish DM, Hamann J, Chen TC, Lin CY, Gordon S, Lin HH. (2007) CD312, the human adhesion-GPCR EMR2, is differentially expressed during differentiation, maturation, and activation of myeloid cells. Biochem Biophys Res Commun, 353 (1): 133-8. [PMID:17174274]

35. Chang GW, Hsiao CC, Peng YM, Vieira Braga FA, Kragten NA, Remmerswaal EB, van de Garde MD, Straussberg R, König GM, Kostenis E et al.. (2016) The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells. Cell Rep, 15 (8): 1757-70. [PMID:27184850]

36. Chang H, Hou P, Wang X, Xiang A, Wu H, Qi W, Yang R, Wang X, Li X, He W et al.. (2023) CD97 negatively regulates the innate immune response against RNA viruses by promoting RNF125-mediated RIG-I degradation. Cell Mol Immunol, 20 (12): 1457-1471. [PMID:37978243]

37. Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M et al.. (2017) Gpr124 is essential for blood-brain barrier integrity in central nervous system disease. Nat Med, 23 (4): 450-460. [PMID:28288111]

38. Chhabra KH, Bathina S, Faniyan TS, Samuel DJ, Raza MU, de Souza Cordeiro LM, Viana Di Prisco G, Atwood BK, Robles J, Bainbridge L et al.. (2024) ADGRL1 is a glucose receptor involved in mediating energy and glucose homeostasis. Diabetologia, 67 (1): 170-189. [PMID:37712955]

39. Chiang NY, Chang GW, Huang YS, Peng YM, Hsiao CC, Kuo ML, Lin HH. (2016) Heparin interacts with the adhesion GPCR GPR56, reduces receptor shedding, and promotes cell adhesion and motility. J Cell Sci, 129 (11): 2156-69. [PMID:27068534]

40. Chiba Y, Yoshizaki K, Saito K, Ikeuchi T, Iwamoto T, Rhodes C, Nakamura T, de Vega S, Morell RJ, Boger ET et al.. (2020) G protein-coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts. J Biol Chem, 295 (45): 15328-15341. [PMID:32868297]

41. Cho C, Smallwood PM, Nathans J. (2017) Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation. Neuron, 95 (5): 1056-1073.e5. [PMID:28803732]

42. Chong ZS, Ohnishi S, Yusa K, Wright GJ. (2018) Pooled extracellular receptor-ligand interaction screening using CRISPR activation. Genome Biol, 19 (1): 205. [PMID:30477585]

43. Cortijo C, Gouzi M, Tissir F, Grapin-Botton A. (2012) Planar cell polarity controls pancreatic Beta cell differentiation and glucose homeostasis. Cell Rep, 2 (6): 1593-606. [PMID:23177622]

44. Das S, Owen KA, Ly KT, Park D, Black SG, Wilson JM, Sifri CD, Ravichandran KS, Ernst PB, Casanova JE. (2011) Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria. Proc Natl Acad Sci USA, 108 (5): 2136-41. [PMID:21245295]

45. Davletov BA, Shamotienko OG, Lelianova VG, Grishin EV, Ushkaryov YA. (1996) Isolation and biochemical characterization of a Ca2+-independent alpha-latrotoxin-binding protein. J Biol Chem, 271 (38): 23239-45. [PMID:8798521]

46. Del Toro D, Carrasquero-Ordaz MA, Chu A, Ruff T, Shahin M, Jackson VA, Chavent M, Berbeira-Santana M, Seyit-Bremer G, Brignani S et al.. (2020) Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons. Cell, 180 (2): 323-339.e19. [PMID:31928845]

47. Demberg LM, Rothemund S, Schöneberg T, Liebscher I. (2015) Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2. Biochem Biophys Res Commun, 464 (3): 743-7. [PMID:26188515]

48. Demberg LM, Winkler J, Wilde C, Simon KU, Schön J, Rothemund S, Schöneberg T, Prömel S, Liebscher I. (2017) Activation of Adhesion G Protein-coupled Receptors: AGONIST SPECIFICITY OF STACHEL SEQUENCE-DERIVED PEPTIDES. J Biol Chem, 292 (11): 4383-4394. [PMID:28154189]

49. Devenport D, Oristian D, Heller E, Fuchs E. (2011) Mitotic internalization of planar cell polarity proteins preserves tissue polarity. Nat Cell Biol, 13 (8): 893-902. [PMID:21743464]

50. Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I et al.. (2011) A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol, 9 (1): e1000582. [PMID:21267068]

51. Duman JG, Mulherkar S, Tu YK, Erikson KC, Tzeng CP, Mavratsas VC, Ho TS, Tolias KF. (2019) The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest. Elife, 8. [PMID:31461398]

52. Eichler W, Hamann J, Aust G. (1997) Expression characteristics of the human CD97 antigen. Tissue Antigens, 50 (5): 429-38. [PMID:9389316]

53. Eubelen M, Bostaille N, Cabochette P, Gauquier A, Tebabi P, Dumitru AC, Koehler M, Gut P, Alsteens D, Stainier DYR et al.. (2018) A molecular mechanism for Wnt ligand-specific signaling. Science, 361 (6403). [PMID:30026314]

54. Favara DM, Banham AH, Harris AL. (2019) ADGRL4/ELTD1 is a highly conserved angiogenesis-associated orphan adhesion GPCR that emerged with the first vertebrates and comprises 3 evolutionary variants. BMC Evol Biol, 19 (1): 143. [PMID:31299890]

55. Florian S, Sonneck K, Czerny M, Hennersdorf F, Hauswirth AW, Bühring HJ, Valent P. (2006) Detection of novel leukocyte differentiation antigens on basophils and mast cells by HLDA8 antibodies. Allergy, 61 (9): 1054-62. [PMID:16918507]

56. Formstone CJ, Little PF. (2001) The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development. Mech Dev, 109: 91-94. [PMID:11677057]

57. Fredriksson R, Lagerström MC, Lundin LG, Schiöth HB. (2003) The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol, 63 (6): 1256-72. [PMID:12761335]

58. Frenster JD, Erdjument-Bromage H, Stephan G, Ravn-Boess N, Wang S, Liu W, Bready D, Wilcox J, Kieslich B, Jankovic M et al.. (2023) PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma. Cell Rep, 42 (7): 112679. [PMID:37354459]

59. Fukuzawa T, Ishida J, Kato A, Ichinose T, Ariestanti DM, Takahashi T, Ito K, Abe J, Suzuki T, Wakana S et al.. (2013) Lung surfactant levels are regulated by Ig-Hepta/GPR116 by monitoring surfactant protein D. PLoS ONE, 8 (7): e69451. [PMID:23922714]

60. Gao W, Long X, Lin X, Deng K, Li D, Huang M, Wang X, Liu Q, Wu M. (2025) Targeting mesenchymal monocyte-derived macrophages to enhance the sensitivity of glioblastoma to temozolomide by inhibiting TNF/CELSR2/p65/Kla-HDAC1/EPAS1 axis. J Adv Res, [Epub ahead of print]. [PMID:40373963]

61. Georgiadi A, Lopez-Salazar V, Merahbi RE, Karikari RA, Ma X, Mourão A, Klepac K, Bühler L, Alfaro AJ, Kaczmarek I et al.. (2021) Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. Nat Commun, 12 (1): 2999. [PMID:34016966]

62. Giera S, Deng Y, Luo R, Ackerman SD, Mogha A, Monk KR, Ying Y, Jeong SJ, Makinodan M, Bialas AR et al.. (2015) The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun, 6: 6121. [PMID:25607655]

63. Gong DM, Zhang YL, Chen DY, Hong LJ, Han F, Liu QB, Jiang JJ, Lu YM. (2018) Endothelial GPR124 Exaggerates the Pathogenesis of Atherosclerosis by Activating Inflammation. Cell Physiol Biochem, 45 (2): 547-557. [PMID:29402834]

64. Gordon S, Hamann J, Lin HH, Stacey M. (2011) F4/80 and the related adhesion-GPCRs. Eur J Immunol, 41 (9): 2472-6. [PMID:21952799]

65. Gromova P, Ralea S, Lefort A, Libert F, Rubin BP, Erneux C, Vanderwinden JM. (2009) Kit K641E oncogene up-regulates Sprouty homolog 4 and trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours. J Cell Mol Med, 13 (8A): 1536-48. [PMID:19453770]

66. Gupte J, Swaminath G, Danao J, Tian H, Li Y, Wu X. (2012) Signaling property study of adhesion G-protein-coupled receptors. FEBS Lett, 586 (8): 1214-9. [PMID:22575658]

67. Hamann J, Aust G, Araç D, Engel FB, Formstone C, Fredriksson R, Hall RA, Harty BL, Kirchhoff C, Knapp B et al.. (2015) International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacol Rev, 67 (2): 338-67. [PMID:25713288]

68. Hamann J, Koning N, Pouwels W, Ulfman LH, van Eijk M, Stacey M, Lin HH, Gordon S, Kwakkenbos MJ. (2007) EMR1, the human homolog of F4/80, is an eosinophil-specific receptor. Eur J Immunol, 37 (10): 2797-802. [PMID:17823986]

69. Hamann J, Kwakkenbos MJ, de Jong EC, Heus H, Olsen AS, van Lier RA. (2003) Inactivation of the EGF-TM7 receptor EMR4 after the Pan-Homo divergence. Eur J Immunol, 33: 1365-1371. [PMID:12731063]

70. Hamann J, Vogel B, van Schijndel GM, van Lier RA. (1996) The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF). J Exp Med, 184 (3): 1185-9. [PMID:9064337]

71. Hamoud N, Tran V, Croteau LP, Kania A, Côté JF. (2014) G-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates. Proc Natl Acad Sci USA, 111 (10): 3745-50. [PMID:24567399]

72. Hsiao CC, Chu TY, Wu CJ, van den Biggelaar M, Pabst C, Hébert J, Kuijpers TW, Scicluna BP, I KY, Chen TC et al.. (2018) The Adhesion G Protein-Coupled Receptor GPR97/ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions. Front Immunol, 9: 2830. [PMID:30559745]

73. Hsiao CC, van der Poel M, van Ham TJ, Hamann J. (2019) Macrophages Do Not Express the Phagocytic Receptor BAI1/ADGRB1. Front Immunol, 10: 962. [PMID:31130954]

74. Huang D, Yu Z, Lu H, Jiang P, Qian X, Han Y, Qian P. (2024) Adhesion GPCR ADGRE2 Maintains Proteostasis to Promote Progression in Acute Myeloid Leukemia. Cancer Res, 84 (13): 2090-2108. [PMID:39082681]

75. Ichtchenko K, Bittner MA, Krasnoperov V, Little AR, Chepurny O, Holz RW, Petrenko AG. (1999) A novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptors. J Biol Chem, 274 (9): 5491-8. [PMID:10026162]

76. Irmscher S, Brix SR, Zipfel SLH, Halder LD, Mutlutürk S, Wulf S, Girdauskas E, Reichenspurner H, Stahl RAK, Jungnickel B et al.. (2019) Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies. Nat Commun, 10 (1): 2961. [PMID:31273197]

77. Jackson VA, Mehmood S, Chavent M, Roversi P, Carrasquero M, Del Toro D, Seyit-Bremer G, Ranaivoson FM, Comoletti D, Sansom MS et al.. (2016) Super-complexes of adhesion GPCRs and neural guidance receptors. Nat Commun, 7: 11184. [PMID:27091502]

78. Jacobson SG, Cideciyan AV, Aleman TS, Sumaroka A, Roman AJ, Gardner LM, Prosser HM, Mishra M, Bech-Hansen NT, Herrera W, Schwartz SB, Liu XZ, Kimberling WJ, Steel KP, Williams DS. (2008) Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism. Hum Mol Genet, 17 (15): 2405-15. [PMID:18463160]

79. Jaspars LH, Vos W, Aust G, Van Lier RA, Hamann J. (2001) Tissue distribution of the human CD97 EGF-TM7 receptor. Tissue Antigens, 57 (4): 325-31. [PMID:11380941]

80. Jones DTD, Dates AN, Rawson SD, Burruss MM, Lipper CH, Blacklow SC. (2023) Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nat Commun, 14 (1): 2490. [PMID:37120430]

81. Küffer A, Lakkaraju AK, Mogha A, Petersen SC, Airich K, Doucerain C, Marpakwar R, Bakirci P, Senatore A, Monnard A et al.. (2016) The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6. Nature, 536 (7617): 464-8. [PMID:27501152]

82. Kane AJ, Sughrue ME, Rutkowski MJ, Phillips JJ, Parsa AT. (2010) EMR-3: a potential mediator of invasive phenotypic variation in glioblastoma and novel therapeutic target. Neuroreport, 21 (16): 1018-22. [PMID:20827226]

83. Kappel DB, Schuch JB, Rovaris DL, da Silva BS, Müller D, Breda V, Teche SP, S Riesgo R, Schüler-Faccini L, Rohde LA et al.. (2019) ADGRL3 rs6551665 as a Common Vulnerability Factor Underlying Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder. Neuromolecular Med, 21 (1): 60-67. [PMID:30652248]

84. Karpus ON, Veninga H, Hoek RM, Flierman D, van Buul JD, Vandenakker CC, vanBavel E, Medof ME, van Lier RA, Reedquist KA et al.. (2013) Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55. J Immunol, 190 (7): 3740-8. [PMID:23447688]

85. Kim JJ, Park YM, Baik KH, Choi HY, Yang GS, Koh I, Hwang JA, Lee J, Lee YS, Rhee H et al.. (2012) Exome sequencing and subsequent association studies identify five amino acid-altering variants influencing human height. Hum Genet, 131 (3): 471-8. [PMID:21959382]

86. Kim YK, Moon S, Hwang MY, Kim DJ, Oh JH, Kim YJ, Han BG, Lee JY, Kim BJ. (2013) Gene-based copy number variation study reveals a microdeletion at 12q24 that influences height in the Korean population. Genomics, 101 (2): 134-8. [PMID:23147675]

87. Knierim AB, Röthe J, Çakir MV, Lede V, Wilde C, Liebscher I, Thor D, Schöneberg T. (2019) Genetic basis of functional variability in adhesion G protein-coupled receptors. Sci Rep, 9 (1): 11036. [PMID:31363148]

88. Kobayashi A, Donaldson DS, Kanaya T, Fukuda S, Baillie JK, Freeman TC, Ohno H, Williams IR, Mabbott NA. (2012) Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations. DNA Res, 19 (5): 407-22. [PMID:22991451]

89. Kop EN, Kwakkenbos MJ, Teske GJ, Kraan MC, Smeets TJ, Stacey M, Lin HH, Tak PP, Hamann J. (2005) Identification of the epidermal growth factor-TM7 receptor EMR2 and its ligand dermatan sulfate in rheumatoid synovial tissue. Arthritis Rheum, 52 (2): 442-50. [PMID:15693006]

90. Kop EN, Matmati M, Pouwels W, Leclercq G, Tak PP, Hamann J. (2009) Differential expression of CD97 on human lymphocyte subsets and limited effect of CD97 antibodies on allogeneic T-cell stimulation. Immunol Lett, 123 (2): 160-8. [PMID:19428565]

91. Kordon SP, Dutka P, Adamska JM, Bandekar SJ, Leon K, Erramilli SK, Adams B, Li J, Kossiakoff AA, Araç D. (2023) Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder. Nat Commun, 14 (1): 635. [PMID:36746957]

92. Kraja AT, Borecki IB, Tsai MY, Ordovas JM, Hopkins PN, Lai CQ, Frazier-Wood AC, Straka RJ, Hixson JE, Province MA et al.. (2013) Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study. Lipids, 48 (2): 155-65. [PMID:23192668]

93. Krasnoperov VG, Bittner MA, Beavis R, Kuang Y, Salnikow KV, Chepurny OG, Little AR, Plotnikov AN, Wu D, Holz RW et al.. (1997) alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor. Neuron, 18 (6): 925-37. [PMID:9208860]

94. Kreienkamp HJ, Zitzer H, Gundelfinger ED, Richter D, Bockers TM. (2000) The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins. J Biol Chem, 275 (42): 32387-90. [PMID:10964907]

95. Kwakkenbos MJ, Chang GW, Lin HH, Pouwels W, de Jong EC, van Lier RA, Gordon S, Hamann J. (2002) The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells. J Leukoc Biol, 71 (5): 854-62. [PMID:11994511]

96. Kwon HS, Kevala K, Qian H, Abu-Asab M, Patnaik S, Marugan J, Kim HY. (2023) Ligand-Induced Activation of GPR110 (ADGRF1) to Improve Visual Function Impaired by Optic Nerve Injury. Int J Mol Sci, 24 (6). [PMID:36982411]

97. Lee J, Hever A, Willhite D, Zlotnik A, Hevezi P. (2005) Effects of RNA degradation on gene expression analysis of human postmortem tissues. FASEB J, 19 (10): 1356-8. [PMID:15955843]

98. Lee JW, Huang BX, Kwon H, Rashid MA, Kharebava G, Desai A, Patnaik S, Marugan J, Kim HY. (2016) Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function. Nat Commun, 7: 13123. [PMID:27759003]

99. Legrand F, Tomasevic N, Simakova O, Lee CC, Wang Z, Raffeld M, Makiya MA, Palath V, Leung J, Baer M et al.. (2014) The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): a novel therapeutic target for eosinophilic disorders. J Allergy Clin Immunol, 133 (5): 1439-47, 1447.e1-8. [PMID:24530099]

100. Lei P, Wang H, Yu L, Xu C, Sun H, Lyu Y, Li L, Zhang DL. (2022) A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets in Uterine Corpus Endometrial cancer. Int Immunopharmacol, 108: 108743. [PMID:35413679]

101. Lei Y, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH. (2014) Identification of novel CELSR1 mutations in spina bifida. PLoS ONE, 9 (3): e92207. [PMID:24632739]

102. Leja J, Essaghir A, Essand M, Wester K, Oberg K, Tötterman TH, Lloyd R, Vasmatzis G, Demoulin JB, Giandomenico V. (2009) Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas. Mod Pathol, 22 (2): 261-72. [PMID:18953328]

103. Lelianova VG, Davletov BA, Sterling A, Rahman MA, Grishin EV, Totty NF, Ushkaryov YA. (1997) Alpha-latrotoxin receptor, latrophilin, is a novel member of the secretin family of G protein-coupled receptors. J Biol Chem, 272 (34): 21504-8. [PMID:9261169]

104. Li J, Lin SM, Qiao JD, Liu XR, Wang J, Jiang M, Zhang J, Zhong M, Chen XQ, Zhu J et al.. (2022) CELSR3 variants are associated with febrile seizures and epilepsy with antecedent febrile seizures. CNS Neurosci Ther, 28 (3): 382-389. [PMID:34951123]

105. Li J, Xie Y, Cornelius S, Jiang X, Sando R, Kordon SP, Pan M, Leon K, Südhof TC, Zhao M et al.. (2020) Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism. Nat Commun, 11 (1): 2140. [PMID:32358586]

106. Li X, Roszko I, Sepich DS, Ni M, Hamm HE, Marlow FL, Solnica-Krezel L. (2013) Gpr125 modulates Dishevelled distribution and planar cell polarity signaling. Development, 140 (14): 3028-39. [PMID:23821037]

107. Liebscher I, Schön J, Petersen SC, Fischer L, Auerbach N, Demberg LM, Mogha A, Cöster M, Simon KU, Rothemund S et al.. (2014) A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133. Cell Rep, 9 (6): 2018-26. [PMID:25533341]

108. Liebscher I, Schöneberg T, Prömel S. (2013) Progress in demystification of adhesion G protein-coupled receptors. Biol Chem, 394 (8): 937-50. [PMID:23518449]

109. Lin H, Xiao P, Bu RQ, Guo S, Yang Z, Yuan D, Zhu ZL, Zhang CX, He QT, Zhang C et al.. (2022) Structures of the ADGRG2-G_s complex in apo and ligand-bound forms. Nat Chem Biol, 18 (11): 1196-1203. [PMID:35982227]

110. Lin HH, Stacey M, Hamann J, Gordon S, McKnight AJ. (2000) Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97. Genomics, 67 (2): 188-200. [PMID:10903844]

111. Lin HH, Stacey M, Stein-Streilein J, Gordon S. (2010) F4/80: the macrophage-specific adhesion-GPCR and its role in immunoregulation. Adv Exp Med Biol, 706: 149-56. [PMID:21618834]

112. Lindenmaier LB, Parmentier N, Guo C, Tissir F, Wright KM. (2019) Dystroglycan is a scaffold for extracellular axon guidance decisions. Elife, 8. [PMID:30758284]

113. Liu D, Duan L, Rodda LB, Lu E, Xu Y, An J, Qiu L, Liu F, Looney MR, Yang Z et al.. (2022) CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells. Science, 375 (6581): eabi5965. [PMID:35143305]

114. Liu Z, Easson GWD, Zhao J, Makki N, Ahituv N, Hilton MJ, Tang SY, Gray RS. (2019) Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant mice. PLoS Genet, 15 (10): e1008096. [PMID:31652254]

115. LopezJimenez ND, Sainz E, Cavenagh MM, Cruz-Ithier MA, Blackwood CA, Battey JF, Sullivan SL. (2005) Two novel genes, Gpr113, which encodes a family 2 G-protein-coupled receptor, and Trcg1, are selectively expressed in taste receptor cells. Genomics, 85 (4): 472-82. [PMID:15780750]

116. Lum AM, Wang BB, Beck-Engeser GB, Li L, Channa N, Wabl M. (2010) Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer. BMC Cancer, 10: 40. [PMID:20149256]

117. Luo R, Jeong SJ, Jin Z, Strokes N, Li S, Piao X. (2011) G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination. Proc Natl Acad Sci USA, 108 (31): 12925-30. [PMID:21768377]

118. Mao C, Zhao RJ, Dong YJ, Gao M, Chen LN, Zhang C, Xiao P, Guo J, Qin J, Shen DD et al.. (2024) Conformational transitions and activation of the adhesion receptor CD97. Mol Cell, 84 (3): 570-583.e7. [PMID:38215752]

119. Marroni F, Pfeufer A, Aulchenko YS, Franklin CS, Isaacs A, Pichler I, Wild SH, Oostra BA, Wright AF, Campbell H, Witteman JC, Kääb S, Hicks AA, Gyllensten U, Rudan I, Meitinger T, Pattaro C, van Duijn CM, Wilson JF, Pramstaller PP, EUROSPAN Consortium. (2009) A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. Circ Cardiovasc Genet, 2 (4): 322-8. [PMID:20031603]

120. Martínez-Gil N, Ovejero D, Garcia-Giralt N, Bruque CD, Mellibovsky L, Nogués X, Rabionet R, Grinberg D, Balcells S. (2022) Genetic Analysis in a Familial Case With High Bone Mineral Density Suggests Additive Effects at Two Loci. JBMR Plus, 6 (4): e10602. [PMID:35434450]

121. Martin M, Vermeiren S, Bostaille N, Eubelen M, Spitzer D, Vermeersch M, Profaci CP, Pozuelo E, Toussay X, Raman-Nair J et al.. (2022) Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders. Science, 375 (6582): eabm4459. [PMID:35175798]

122. Mathiasen S, Palmisano T, Perry NA, Stoveken HM, Vizurraga A, McEwen DP, Okashah N, Langenhan T, Inoue A, Lambert NA et al.. (2020) G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3. Nat Chem Biol, 16 (12): 1343-1350. [PMID:32778842]

123. Matmati M, Pouwels W, van Bruggen R, Jansen M, Hoek RM, Verhoeven AJ, Hamann J. (2007) The human EGF-TM7 receptor EMR3 is a marker for mature granulocytes. J Leukoc Biol, 81 (2): 440-8. [PMID:17108056]

124. McKnight AJ, Macfarlane AJ, Dri P, Turley L, Willis AC, Gordon S. (1996) Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family. J Biol Chem, 271 (1): 486-9. [PMID:8550607]

125. Mogha A, Benesh AE, Patra C, Engel FB, Schöneberg T, Liebscher I, Monk KR. (2013) Gpr126 functions in Schwann cells to control differentiation and myelination via G-protein activation. J Neurosci, 33 (46): 17976-85. [PMID:24227709]

126. Monk KR, Naylor SG, Glenn TD, Mercurio S, Perlin JR, Dominguez C, Moens CB, Talbot WS. (2009) A G protein-coupled receptor is essential for Schwann cells to initiate myelination. Science, 325 (5946): 1402-5. [PMID:19745155]

127. Monk KR, Oshima K, Jörs S, Heller S, Talbot WS. (2011) Gpr126 is essential for peripheral nerve development and myelination in mammals. Development, 138 (13): 2673-80. [PMID:21613327]

128. Müller A, Winkler J, Fiedler F, Sastradihardja T, Binder C, Schnabel R, Kungel J, Rothemund S, Hennig C, Schöneberg T et al.. (2015) Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1. PLoS Genet, 11 (10): e1005624. [PMID:26505631]

129. Ni YY, Chen Y, Lu SY, Sun BY, Wang F, Wu XL, Dang SY, Zhang GH, Zhang HX, Kuang Y et al.. (2014) Deletion of Gpr128 results in weight loss and increased intestinal contraction frequency. World J Gastroenterol, 20 (2): 498-508. [PMID:24574718]

130. Nishimura T, Honda H, Takeichi M. (2012) Planar cell polarity links axes of spatial dynamics in neural-tube closure. Cell, 149 (5): 1084-97. [PMID:22632972]

131. Nybo ML, Kvam JM, Nielsen JE, Frederiksen H, Spiess K, Jensen KHR, Gadgaard S, Walser ALS, Thomsen JS, Cowin P et al.. (2023) Loss of Adgra3 causes obstructive azoospermia with high penetrance in male mice. FASEB J, 37 (2): e22781. [PMID:36688818]

132. O'Sullivan ML, de Wit J, Savas JN, Comoletti D, Otto-Hitt S, Yates 3rd JR, Ghosh A. (2012) FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development. Neuron, 73 (5): 903-10. [PMID:22405201]

133. Pan Y, Liu G, Wang D, Li Y. (2019) Analysis of lncRNA-Mediated ceRNA Crosstalk and Identification of Prognostic Signature in Head and Neck Squamous Cell Carcinoma. Front Pharmacol, 10: 150. [PMID:30886579]

134. Park D, Tosello-Trampont AC, Elliott MR, Lu M, Haney LB, Ma Z, Klibanov AL, Mandell JW, Ravichandran KS. (2007) BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature, 450 (7168): 430-4. [PMID:17960134]

135. Patat O, Pagin A, Siegfried A, Mitchell V, Chassaing N, Faguer S, Monteil L, Gaston V, Bujan L, Courtade-Saïdi M et al.. (2016) Truncating Mutations in the Adhesion G Protein-Coupled Receptor G2 Gene ADGRG2 Cause an X-Linked Congenital Bilateral Absence of Vas Deferens. Am J Hum Genet, 99 (2): 437-42. [PMID:27476656]

136. Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, Mogha A, Monk KR, Mühlfeld C, Engel FB. (2013) Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent. Proc Natl Acad Sci USA, 110 (42): 16898-903. [PMID:24082093]

137. Pederick DT, Lui JH, Gingrich EC, Xu C, Wagner MJ, Liu Y, He Z, Quake SR, Luo L. (2021) Reciprocal repulsions instruct the precise assembly of parallel hippocampal networks. Science, 372 (6546): 1068-1073. [PMID:34083484]

138. Pederick DT, Perry-Hauser NA, Meng H, He Z, Javitch JA, Luo L. (2023) Context-dependent requirement of G protein coupling for Latrophilin-2 in target selection of hippocampal axons. Elife, 12. [PMID:36939320]

139. Petersen SC, Luo R, Liebscher I, Giera S, Jeong SJ, Mogha A, Ghidinelli M, Feltri ML, Schöneberg T, Piao X et al.. (2015) The adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with laminin-211. Neuron, 85 (4): 755-69. [PMID:25695270]

140. Piao X, Hill RS, Bodell A, Chang BS, Basel-Vanagaite L, Straussberg R, Dobyns WB, Qasrawi B, Winter RM, Innes AM et al.. (2004) G protein-coupled receptor-dependent development of human frontal cortex. Science, 303 (5666): 2033-6. [PMID:15044805]

141. Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H et al.. (2021) Structures of the glucocorticoid-bound adhesion receptor GPR97-G_o complex. Nature, 589 (7843): 620-626. [PMID:33408414]

142. Ping YQ, Xiao P, Yang F, Zhao RJ, Guo SC, Yan X, Wu X, Zhang C, Lu Y, Zhao F et al.. (2022) Structural basis for the tethered peptide activation of adhesion GPCRs. Nature, 604 (7907): 763-770. [PMID:35418678]

143. Popova NV, Plotnikov A, Deev IE, Petrenko AG. (2007) Interaction of calcium-independent latrotoxin receptor with intracellular adapter protein TRIP8b. Dokl Biochem Biophys, 414: 149-51. [PMID:17695324]

144. Popova NV, Plotnikov AN, Ziganshin RKh, Deyev IE, Petrenko AG. (2008) Analysis of proteins interacting with TRIP8b adapter. Biochemistry Mosc, 73 (6): 644-51. [PMID:18620529]

145. Posokhova E, Shukla A, Seaman S, Volate S, Hilton MB, Wu B, Morris H, Swing DA, Zhou M, Zudaire E et al.. (2015) GPR124 functions as a WNT7-specific coactivator of canonical β-catenin signaling. Cell Rep, 10 (2): 123-30. [PMID:25558062]

146. Prömel S, Waller-Evans H, Dixon J, Zahn D, Colledge WH, Doran J, Carlton MB, Grosse J, Schöneberg T, Russ AP et al.. (2012) Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Dev Dyn, 241 (10): 1591-602. [PMID:22837050]

147. Purcell RH, Toro C, Gahl WA, Hall RA. (2017) A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity. Hum Mutat, 38 (12): 1751-1760. [PMID:28891236]

148. Qian Y, Ma Z, Liu C, Li X, Zhu X, Wang N, Xu Z, Xia R, Liang J, Duan Y et al.. (2022) Structural insights into adhesion GPCR ADGRL3 activation and G_q, G_s, G_i, and G₁₂ coupling. Mol Cell, 82 (22): 4340-4352.e6. [PMID:36309016]

149. Qu X, Qiu N, Wang M, Zhang B, Du J, Zhong Z, Xu W, Chu X, Ma L, Yi C et al.. (2022) Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature, 604 (7907): 779-785. [PMID:35418679]

150. Rahman MA, Ashton AC, Meunier FA, Davletov BA, Dolly JO, Ushkaryov YA. (1999) Norepinephrine exocytosis stimulated by alpha-latrotoxin requires both external and stored Ca2+ and is mediated by latrophilin, G proteins and phospholipase C. Philos Trans R Soc Lond, B, Biol Sci, 354 (1381): 379-86. [PMID:10212487]

151. Ravenscroft G, Nolent F, Rajagopalan S, Meireles AM, Paavola KJ, Gaillard D, Alanio E, Buckland M, Arbuckle S, Krivanek M et al.. (2015) Mutations of GPR126 are responsible for severe arthrogryposis multiplex congenita. Am J Hum Genet, 96 (6): 955-61. [PMID:26004201]

152. Ravn-Boess N, Roy N, Hattori T, Bready D, Donaldson H, Lawson C, Lapierre C, Korman A, Rodrick T, Liu E et al.. (2023) The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability. Cell Rep, 42 (11): 113374. [PMID:37938973]

153. Regard JB, Sato IT, Coughlin SR. (2008) Anatomical profiling of G protein-coupled receptor expression. Cell, 135 (3): 561-71. [PMID:18984166]

154. Reiners J, van Wijk E, Märker T, Zimmermann U, Jürgens K, te Brinke H, Overlack N, Roepman R, Knipper M, Kremer H et al.. (2005) Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2. Hum Mol Genet, 14 (24): 3933-43. [PMID:16301216]

155. Sabik OL, Calabrese GM, Taleghani E, Ackert-Bicknell CL, Farber CR. (2020) Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS Data. Cell Rep, 32 (11): 108145. [PMID:32937138]

156. Salašová A, Yokota C, Potěšil D, Zdráhal Z, Bryja V, Arenas E. (2017) A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway. Mol Neurodegener, 12 (1): 54. [PMID:28697798]

157. Scholz N, Gehring J, Guan C, Ljaschenko D, Fischer R, Lakshmanan V, Kittel RJ, Langenhan T. (2015) The adhesion GPCR latrophilin/CIRL shapes mechanosensation. Cell Rep, 11 (6): 866-874. [PMID:25937282]

158. Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW et al.. (2007) Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature, 449 (7160): 346-50. [PMID:17882221]

159. Shi W, Xu C, Lei P, Sun X, Song M, Guo Y, Song W, Li Y, Yu L, Zhang H et al.. (2024) A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets for breast cancer. Breast Cancer Res Treat, 207 (2): 417-434. [PMID:38834774]

160. Shima Y, Kawaguchi SY, Kosaka K, Nakayama M, Hoshino M, Nabeshima Y, Hirano T, Uemura T. (2007) Opposing roles in neurite growth control by two seven-pass transmembrane cadherins. Nat Neurosci, 10 (8): 963-9. [PMID:17618280]

161. Silva JP, Lelianova VG, Ermolyuk YS, Vysokov N, Hitchen PG, Berninghausen O, Rahman MA, Zangrandi A, Fidalgo S, Tonevitsky AG et al.. (2011) Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities. Proc Natl Acad Sci USA, 108 (29): 12113-8. [PMID:21724987]

162. Slepak TI, Guyot M, Walters W, Eichberg DG, Ivan ME. (2023) Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation. J Biol Chem, 299 (9): 105105. [PMID:37517698]

163. Southern C, Cook JM, Neetoo-Isseljee Z, Taylor DL, Kettleborough CA, Merritt A, Bassoni DL, Raab WJ, Quinn E, Wehrman TS et al.. (2013) Screening β-Arrestin Recruitment for the Identification of Natural Ligands for Orphan G-Protein-Coupled Receptors. J Biomol Screen, 18 (5): 599-609. [PMID:23396314]

164. Stacey M, Chang GW, Davies JQ, Kwakkenbos MJ, Sanderson RD, Hamann J, Gordon S, Lin HH. (2003) The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans. Blood, 102 (8): 2916-24. [PMID:12829604]

165. Stacey M, Chang GW, Sanos SL, Chittenden LR, Stubbs L, Gordon S, Lin HH. (2002) EMR4, a novel epidermal growth factor (EGF)-TM7 molecule up-regulated in activated mouse macrophages, binds to a putative cellular ligand on B lymphoma cell line A20. J Biol Chem, 277 (32): 29283-93. [PMID:12023293]

166. Stacey M, Lin HH, Hilyard KL, Gordon S, McKnight AJ. (2001) Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils. J Biol Chem, 276 (22): 18863-70. [PMID:11279179]

167. Steichen H, Xue J, Zaidman NA. (2025) Identification and localization of adhesion G protein-coupled receptor expression in the murine kidney. Am J Physiol Renal Physiol, 329 (1): F11-F19. [PMID:40372763]

168. Stoveken HM, Bahr LL, Anders MW, Wojtovich AP, Smrcka AV, Tall GG. (2016) Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein-Coupled Receptor Antagonist. Mol Pharmacol, 90 (3): 214-24. [PMID:27338081]

169. Stoveken HM, Hajduczok AG, Xu L, Tall GG. (2015) Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist. Proc Natl Acad Sci USA, 112 (19): 6194-9. [PMID:25918380]

170. Stoveken HM, Larsen SD, Smrcka AV, Tall GG. (2018) Gedunin- and Khivorin-Derivatives Are Small-Molecule Partial Agonists for Adhesion G Protein-Coupled Receptors GPR56/ADGRG1 and GPR114/ADGRG5. Mol Pharmacol, 93 (5): 477-488. [PMID:29476042]

171. Sun J, Kranzler HR, Gelernter J, Bi J. (2020) A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction. J Psychiatry Neurosci, 45 (1): 34-44. [PMID:31490055]

172. Sun P, He L, Jia K, Yue Z, Li S, Jin Y, Li Z, Siwko S, Xue F, Su J et al.. (2020) Regulation of body length and bone mass by Gpr126/Adgrg6. Sci Adv, 6 (12): eaaz0368. [PMID:32219165]

173. Tang X, Jin R, Qu G, Wang X, Li Z, Yuan Z, Zhao C, Siwko S, Shi T, Wang P et al.. (2013) GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway. Cancer Res, 73 (20): 6206-18. [PMID:24008316]

174. Thakar S, Wang L, Yu T, Ye M, Onishi K, Scott J, Qi J, Fernandes C, Han X, Yates 3rd JR et al.. (2017) Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation. Proc Natl Acad Sci USA, 114 (4): E610-E618. [PMID:28057866]

175. Tissir F, De-Backer O, Goffinet AM, Lambert de Rouvroit C. (2002) Developmental expression profiles of Celsr (Flamingo) genes in the mouse. Mech Dev, 112 (1-2): 157-60. [PMID:11850187]

176. Torregrosa-Carrión R, Piñeiro-Sabarís R, Siguero-Álvarez M, Grego-Bessa J, Luna-Zurita L, Fernandes VS, MacGrogan D, Stainier DYR, de la Pompa JL. (2021) Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development. Sci Adv, 7 (46): eabj5445. [PMID:34767447]

177. Tu YK, Duman JG, Tolias KF. (2018) The Adhesion-GPCR BAI1 Promotes Excitatory Synaptogenesis by Coordinating Bidirectional Trans-synaptic Signaling. J Neurosci, 38 (39): 8388-8406. [PMID:30120207]

178. Tönjes A, Koriath M, Schleinitz D, Dietrich K, Böttcher Y, Rayner NW, Almgren P, Enigk B, Richter O, Rohm S, Fischer-Rosinsky A, Pfeiffer A, Hoffmann K, Krohn K, Aust G, Spranger J, Groop L, Blüher M, Kovacs P, Stumvoll M. (2009) Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs. Hum Mol Genet, 18 (23): 4662-8. [PMID:19729412]

179. Vallon M, Essler M. (2006) Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. J Biol Chem, 281 (45): 34179-88. [PMID:16982628]

180. Vallon M, Yuki K, Nguyen TD, Chang J, Yuan J, Siepe D, Miao Y, Essler M, Noda M, Garcia KC et al.. (2018) A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability. Cell Rep, 25 (2): 339-349.e9. [PMID:30304675]

181. van Eijk M, Aust G, Brouwer MS, van Meurs M, Voerman JS, Dijke IE, Pouwels W, Sändig I, Wandel E, Aerts JM, Boot RG, Laman JD, Hamann J. (2010) Differential expression of the EGF-TM7 family members CD97 and EMR2 in lipid-laden macrophages in atherosclerosis, multiple sclerosis and Gaucher disease. Immunol Lett, 129 (2): 64-71. [PMID:20167235]

182. van Wijk E, van der Zwaag B, Peters T, Zimmermann U, Te Brinke H, Kersten FF, Märker T, Aller E, Hoefsloot LH, Cremers CW et al.. (2006) The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1. Hum Mol Genet, 15 (5): 751-65. [PMID:16434480]

183. Vanhollebeke B, Stone OA, Bostaille N, Cho C, Zhou Y, Maquet E, Gauquier A, Cabochette P, Fukuhara S, Mochizuki N et al.. (2015) Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis. Elife, 4. [PMID:26051822]

184. Vanti WB, Nguyen T, Cheng R, Lynch KR, George SR, O'Dowd BF. (2003) Novel human G-protein-coupled receptors. Biochem Biophys Res Commun, 305 (1): 67-71. [PMID:12732197]

185. Veninga H, Becker S, Hoek RM, Wobus M, Wandel E, van der Kaa J, van der Valk M, de Vos AF, Haase H, Owens B et al.. (2008) Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration. J Immunol, 181 (9): 6574-83. [PMID:18941248]

186. Vilboux T, Malicdan MC, Roney JC, Cullinane AR, Stephen J, Yildirimli D, Bryant J, Fischer R, Vemulapalli M, Mullikin JC et al.. (2017) CELSR2, encoding a planar cell polarity protein, is a putative gene in Joubert syndrome with cortical heterotopia, microophthalmia, and growth hormone deficiency. Am J Med Genet A, 173 (3): 661-666. [PMID:28052552]

187. Vitobello A, Mazel B, Lelianova VG, Zangrandi A, Petitto E, Suckling J, Salpietro V, Meyer R, Elbracht M, Kurth I et al.. (2022) ADGRL1 haploinsufficiency causes a variable spectrum of neurodevelopmental disorders in humans and alters synaptic activity and behavior in a mouse model. Am J Hum Genet, 109 (8): 1436-1457. [PMID:35907405]

188. Vizurraga AL, Robertson MJ, Yu M, Skiniotis G, Tall GG. (2023) Hexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56. Mol Pharmacol, 104 (1): 28-41. [PMID:37290962]

189. Volynski KE, Capogna M, Ashton AC, Thomson D, Orlova EV, Manser CF, Ribchester RR, Ushkaryov YA. (2003) Mutant alpha-latrotoxin (LTXN4C) does not form pores and causes secretion by receptor stimulation: this action does not require neurexins. J Biol Chem, 278 (33): 31058-66. [PMID:12782639]

190. Waller-Evans H, Prömel S, Langenhan T, Dixon J, Zahn D, Colledge WH, Doran J, Carlton MB, Davies B, Aparicio SA et al.. (2010) The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse. PLoS ONE, 5 (11): e14047. [PMID:21124978]

191. Wandel E, Saalbach A, Sittig D, Gebhardt C, Aust G. (2012) Thy-1 (CD90) is an interacting partner for CD97 on activated endothelial cells. J Immunol, 188 (3): 1442-50. [PMID:22210915]

192. Wang F, Wang Y, Qiu W, Zhang Q, Yang H, Song G. (2023) Crystal Structure of the Extracellular Domains of GPR110. J Mol Biol, 435 (6): 167979. [PMID:36716818]

193. Wang J, Miao Y, Wicklein R, Sun Z, Wang J, Jude KM, Fernandes RA, Merrill SA, Wernig M, Garcia KC et al.. (2021) RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development. Cell, 184 (24): 5869-5885.e25. [PMID:34758294]

194. Wang N, Qian Y, Xia R, Zhu X, Xiong Y, Zhang A, Guo C, He Y. (2023) Structural basis of CD97 activation and G-protein coupling. Cell Chem Biol, 30 (11): 1343-1353.e5. [PMID:37673067]

195. Wang S, Mandell JD, Kumar Y, Sun N, Morris MT, Arbelaez J, Nasello C, Dong S, Duhn C, Zhao X et al.. (2018) De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis. Cell Rep, 24 (13): 3441-3454.e12. [PMID:30257206]

196. Wang T, Ward Y, Tian L, Lake R, Guedez L, Stetler-Stevenson WG, Kelly K. (2005) CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells. Blood, 105 (7): 2836-44. [PMID:15576472]

197. Ward Y, Lake R, Martin PL, Killian K, Salerno P, Wang T, Meltzer P, Merino M, Cheng SY, Santoro M et al.. (2013) CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model. Oncogene, 32 (22): 2726-38. [PMID:22797060]

198. Ward Y, Lake R, Yin JJ, Heger CD, Raffeld M, Goldsmith PK, Merino M, Kelly K. (2011) LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells. Cancer Res, 71 (23): 7301-11. [PMID:21978933]

199. Wilde C, Chaudhry PM, Luo R, Simon KU, Piao X, Liebscher I. (2023) Collagen VI Is a Gi-Biased Ligand of the Adhesion GPCR GPR126/ADGRG6. Cells, 12 (11). [PMID:37296671]

200. Wilde C, Fischer L, Lede V, Kirchberger J, Rothemund S, Schöneberg T, Liebscher I. (2016) The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist. FASEB J, 30 (2): 666-73. [PMID:26499266]

201. Willsey AJ, Fernandez TV, Yu D, King RA, Dietrich A, Xing J, Sanders SJ, Mandell JD, Huang AY, Richer P et al.. (2017) De Novo Coding Variants Are Strongly Associated with Tourette Disorder. Neuron, 94 (3): 486-499.e9. [PMID:28472652]

202. Wu M, Lo TH, Li L, Sun J, Deng C, Chan KY, Li X, Yeh ST, Lee JTH, Lui PPY et al.. (2023) Amelioration of non-alcoholic fatty liver disease by targeting adhesion G protein-coupled receptor F1 (Adgrf1). Elife, 12. [PMID:37580962]

203. Xiao P, Guo S, Wen X, He QT, Lin H, Huang SM, Gou L, Zhang C, Yang Z, Zhong YN et al.. (2022) Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature, 604 (7907): 771-778. [PMID:35418677]

204. Xu L, Begum S, Hearn JD, Hynes RO. (2006) GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proc Natl Acad Sci USA, 103 (24): 9023-8. [PMID:16757564]

205. Xu Y, Fang X, Zhao Z, Wu H, Fan H, Zhang Y, Meng Q, Rong Q, Fukunaga K, Guo Q et al.. (2024) GPR124 induces NLRP3 inflammasome-mediated pyroptosis in endothelial cells during ischemic injury. Eur J Pharmacol, 962: 176228. [PMID:38042462]

206. Yang MY, Hilton MB, Seaman S, Haines DC, Nagashima K, Burks CM, Tessarollo L, Ivanova PT, Brown HA, Umstead TM et al.. (2013) Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116. Cell Rep, 3 (5): 1457-64. [PMID:23684610]

207. Yang Z, Ping YQ, Wang MW, Zhang C, Zhou SH, Xi YT, Zhu KK, Ding W, Zhang QY, Song ZC et al.. (2025) Identification, structure, and agonist design of an androgen membrane receptor. Cell, 188 (6): 1589-1604.e24. [PMID:39884271]

208. Yeung J, Adili R, Stringham EN, Luo R, Vizurraga A, Rosselli-Murai LK, Stoveken HM, Yu M, Piao X, Holinstat M et al.. (2020) GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force. Proc Natl Acad Sci U S A, 117 (45): 28275-28286. [PMID:33097663]

209. Yin GN, Kim DK, Kang JI, Im Y, Lee DS, Han AR, Ock J, Choi MJ, Kwon MH, Limanjaya A et al.. (2022) Latrophilin-2 is a novel receptor of LRG1 that rescues vascular and neurological abnormalities and restores diabetic erectile function. Exp Mol Med, 54 (5): 626-638. [PMID:35562586]

210. Yona S, Lin HH, Siu WO, Gordon S, Stacey M. (2008) Adhesion-GPCRs: emerging roles for novel receptors. Trends Biochem Sci, 33 (10): 491-500. [PMID:18789697]

211. Yoon JH, Cho SG. (2020) ADGRF4 Regulates Non-small Cell Lung Cancer Cell Invasiveness. Anticancer Res, 40 (12): 6835-6844. [PMID:33288575]

212. Zaidman NA, Tomilin VN, Hassanzadeh Khayyat N, Damarla M, Tidmore J, Capen DE, Brown D, Pochynyuk OM, Pluznick JL. (2020) Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion. Proc Natl Acad Sci U S A, 117 (42): 26470-26481. [PMID:33004624]

213. Zhan D, Yang Z, Li P, Pan J. (2025) Therapeutic targets for gastrointestinal diseases: proteome-wide Mendelian randomization and colocalization analyses. Postgrad Med J, 101 (1194): 283-290. [PMID:39400547]

214. Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF et al.. (2018) Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility. Elife, 7. [PMID:29393851]

215. Zhang XH, Shen CL, Wang XY, Xiong WF, Shang X, Tang LY, Zhang HX, Wan YH, Wu YB, Fei J et al.. (2022) Increased Anxiety-like Behaviors in Adgra1^-/- Male But Not Female Mice are Attributable to Elevated Neuron Dendrite Density, Upregulated PSD95 Expression, and Abnormal Activation of the PI3K/AKT/GSK-3β and MEK/ERK Pathways. Neuroscience, 503: 131-145. [PMID:36115515]

216. Zhang XH, Tang LY, Wang XY, Shen CL, Xiong WF, Shen Y, Wan YH, Wu YB, Wang YC, Zhang HX et al.. (2021) ADGRA1 negatively regulates energy expenditure and thermogenesis through both sympathetic nervous system and hypothalamus-pituitary-thyroid axis in male mice. Cell Death Dis, 12 (4): 362. [PMID:33824276]

217. Zhou S, Lin W, Jin X, Niu R, Yuan Z, Chai T, Zhang Q, Guo M, Kim SS, Liu M et al.. (2024) CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells. Cell Rep Med, 5 (12): 101844. [PMID:39637858]

218. Zhou X, Lei S, Li L, Xu T, Gu W, Ma F, Yang R. (2021) [Peripheral blood EMR3 gene methylation level is correlated with breast cancer in Chinese women]. Nan Fang Yi Ke Da Xue Xue Bao, 41 (10): 1456-1463. [PMID:34755660]

219. Zhou Y, Nathans J. (2014) Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling. Dev Cell, 31 (2): 248-56. [PMID:25373781]

220. Zhu B, Luo R, Jin P, Li T, Oak HC, Giera S, Monk KR, Lak P, Shoichet BK, Piao X. (2019) GAIN domain-mediated cleavage is required for activation of G protein-coupled receptor 56 (GPR56) by its natural ligands and a small-molecule agonist. J Biol Chem, 294 (50): 19246-19254. [PMID:31628191]

221. Zhu D, Osuka S, Zhang Z, Reichert ZR, Yang L, Kanemura Y, Jiang Y, You S, Zhang H, Devi NS et al.. (2018) BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation. Cancer Cell, 33 (6): 1004-1016.e5. [PMID:29894688]

222. Zhu X, Qian Y, Li X, Xu Z, Xia R, Wang N, Liang J, Yin H, Zhang A, Guo C et al.. (2022) Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13 (1): 5513. [PMID:36127364]

223. Zuko A, Oguro-Ando A, Post H, Taggenbrock RL, van Dijk RE, Altelaar AF, Heck AJ, Petrenko AG, van der Zwaag B, Shimoda Y et al.. (2016) Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis. Front Mol Neurosci, 9: 143. [PMID:28018171]

Demet Arac-Ozkan (Past contributor) Department of Biochemistry and Molecular Biology University of Chicago 929 E. 57th Street GCIS W210 Chicago, IL 60637 USA Gabriela Aust (Past contributor) Department of Surgery University of Leipzig Liebigstr. 20 04103 Leipzig Germany Tom I. Bonner (Past contributor, retired) (Past Core Member) Special Volunteer Office of Science Director NIMH Bethesda MD USA Heike Cappallo-Obermann (Past contributor) University Hospital Hamburg-Eppendorf Department of Andrology Martinistrasse 52 20246 Hamburg Germany Caroline Formstone (Past contributor) MRC Centre for Developmental Neurobiology King's College London New Hunt's House, 4th Floor Guy's Hospital Campus London SE1 1UL UK Jörg Hamann (Past contributor) Academic Medical Center University of Amsterdam Meibergdreef 9 1105AZ Amsterdam The Netherlands Breanne Harty (Past contributor) Washington University School of Medicine Dept of Developmental Biology 660 S. Euclid Ave St. Louis MO 63130 USA Henrike Heyne (Past contributor) Institute of Biochemistry Medical Faculty University of Leipzig Johannisallee 30 04103 Leipzig Germany Christiane Kirchhoff (Past contributor) University Hospital Hamburg-Eppendorf Department of Andrology Martinistrasse 52 20246 Hamburg Germany Barbara Knapp (Past contributor) Johannes-Gutenberg Universitaet Mainz Institut fuer Zoologie, Abt. I - AG Wolfrum Muellerweg 6 D-55099 Mainz Germany Arunkumar Krishnan (Past contributor) Department of Neuroscience Biomedical Center Box 593 75 124 Uppsala Sweden Tobias Langenhan (Past contributor) Division of General Biochemistry Rudolf-Schönheimer-Institute of Biochemistry University of Leipzig Johannisallee 3004103 Leipzig Germany Diana Le Duc (Past contributor) Institute of Biochemistry Medical Faculty University of Leipzig Johannisallee 30 04103 Leipzig Germany Ines Liebscher Leipzig University Leipzig Sachsen Germany Hsi-Hsien Lin (Past contributor) Department of Microbiology and Immunology College of Medicine Chang Gung University 259 Wen-Hwa 1st Road Kwei-Shan Tao-Yuan Taiwan David C. Martinelli (Past contributor) 265 Campus Drive Stanford California, 94305 USA Kelly Monk (Past contributor) Washington University School of Medicine Dept of Developmental Biology 660 S. Euclid Ave St. Louis MO 63130 USA Nicole A. Perry-Hauser University of Glasgow Molecular Biosciences Glasgow UK Xianhua Piao (Past contributor) Boston Children's Hospital Department of Newborn Medicine 300 Longwood Avenue Boston MA 02115, USA Simone Prömel (Past contributor) Institute of Biochemistry Medical Faculty University of Leipzig Johannisallee 30 04103 Leipzig Germany Helgi Schiöth Dept. of Neuroscience Biomedical Centre Uppsala University Uppsala Sweden Nicole Scholz Leipzig University Leipzig Sachsen Germany Torsten Schöneberg (Past contributor) Institute of Biochemistry Medical Faculty University of Leipzig Johannisallee 30 04103 Leipzig Germany Kathleen Singer (Past contributor) Boston Children's Hospital Department of GI/Nutrition 300 Longwood Avenue Boston MA 02115, USA Martin Stacey (Past contributor) Institute of Molecular and Cellular Biology Garstang 8.54 University of Leeds Leeds, LS2 9JT UK Yuri Ushkaryov (Past contributor) Medway School of Pharmacy University of Kent Central Avenue Anson Building Chatham Maritime ME4 4TB UK Uwe Wolfrum (Past contributor) Johannes-Gutenberg Universitaet Mainz Institut fuer Zoologie, Abt. I - AG Wolfrum Muellerweg 6 D-55099 Mainz Germany Lei Xu (Past contributor) 601 Elmwood Ave. Department of Biomedical Genetics University of Rochester Medical Center Rochester NY 14642, USA Nathan Zaidman University of New Mexico (UNM) Albuquerque, New Mexico USA